Efficacy of Pregnenolone

Pregnenolone supplements have been clinically studied and proven to be effective against mental degeneration, fatigue, depression-related symptoms, and stress. Pregnenolone is a precursor to many important hormones and is known to help improve mental abilities, such as memory, alertness, and mood. Research remains inconclusive, but there are reports that pregnenolone supplements may also help prevent discomfort that is associated with arthritis and menopause.

Pregnenolone Supplement Studies Conducted with Positive Results

Studies have shown that pregnenolone supplements may significantly decrease depression-related symptoms in individuals with bi-polar disorder.(1) The essential compounds found in pregnenolone help stabilize mood and balance hormones, which can greatly improve normal brain functions. However, it is suggested that pregnenolone may help adult men and women of all ages stabilize their mood and balance hormones, not just those diagnosed with bi-polar disorder.

In another study(2) that was conducted by medical professionals, 27 patients with depression and 10 healthy volunteers were surveyed. It was found that the patients with depression had lower levels of pregnenolone than the other 10 healthy individuals. The study concluded that people with normal levels of pregnenolone experience:

  • Improved sleep quality
  • Increased alertness
  • Balanced and healthy mood
  • Reduced depression, stress, and anxiety

(1)A Randomized, Double-Blind, Placebo-Controlled Trial of Pregnenolone;NCBI;11 January 2014.

(2)Recharge With Pregnenolone;LE Magazine; June 2004.